血清人绒毛膜促性腺激素水平在几种常见妇科疾病中的诊断价值

摘要

Objeetive To explore the diagnosis value of serumβ-HCG concentration detected by chemiluminescent immunoassay in several common gynecological Diseases,Methods To make a statistical analysis of theβ-HCG results of each group,Reults Comparing the results of each group,the concentrations ofβ-HCG in the normal early pregnancy group appears much lower than other groups,There is great statistical significance among these groups with P＜0,05；But there is not much difference of β-HCG between hydatidiform mole group and invasive hydatidiform mole group with P＞0.05；while the value of β-HCG of Choriocareinoma group is much higher than the other groups with obvious statistical significance(P＜0.01).Conclusion It is very important to make the continuous detection of β-HCG in differential diagnosis,prognosis,clinical stages or the diagnosis in Gestational trophoblastic diseases.And it should be considered combined with the pathology,B-type Ultrasonic and computed tomography.%目的 探讨人绒毛膜促性腺激素(β-HCG)在几种常见妇科疾病诊断中的应用价值.方法 应用化学发光免疫分析法(CLIA)测定深圳地区几种常见妇科疾病患者血清β-HCG水平,并对病例中的各组结果进行统计学分析.结果 葡萄胎组、侵蚀性葡萄胎组及绒毛膜癌各组β-HCG含量明显高于正常早期妊娠组,差异有统计学意义(P＜0.01),经手术治疗后争HCG含量可迅速回复正常范围之内；葡萄胎组及侵蚀性葡萄胎组两者之间β-HCG含量相比较,差异无统计学意义(P＞0.05)；绒毛膜癌β-HCG含量明显高于葡萄胎组、侵蚀性葡萄胎组,差异有统计学意义(P＜0.05).结论 β-HCG在葡萄胎、侵蚀性葡萄胎、绒毛膜癌的诊断、鉴别诊断、转归、预后及临床分期中具有重要意义,但其诊断仍须结合B超、CT及病理诊断.