Angio－OCT 与 FD－OCT 的眼底检查相关性分析

摘要

目的：比较两种光学相干断层成像术（ optical coherence tomography ，OCT）：血流成像光学相干断层成像术（ Angio－optical coherence tomography ， Angio－OCT）和傅立叶域光学相干断层成像术（ Fourier domain－optical coherence tomography ， FD－OCT）眼底检查的相关性及差异性。方法：分别用Angio－OCT和FD－OCT测量20例受试者双眼神经纤维层厚度、视盘各参数和节细胞复合体厚度等，并对两种仪器测量值进行比较，采用Pearson相关分析研究两种仪器测量值的相关性，用配对样本t检验比较两种仪器测量值的差异性。结果：（1）两种OCT所测RNFL厚度、视盘参数及GCC厚度，总体相关性为0．7～0．8。（2） Angio－OCT 所测GCC厚度比FD－OCT所测平均值高，但其它参数如RNFL厚度、视盘面积等，Angio－OCT的测量值普遍比FD－OCT的测量值低。结论：两种OCT的测量值（ RNFL厚度、视盘参数、GCC厚度）有一定相关性，但不能直接比较。%?AIM:To compare the coherence and difference on the fundus examination made with two kinds of optical coherence tomography ( OCT): Angio-OCT and fourier domain-optical coherence tomography ( FD-OCT) .?METHODS:Using Angio-OCT and FD-OCT to measure the retinal nerve fiber layer ( RNFL ) thickness, optic parameters, and ganglion cell complexes ( GCC ) thickness from 20 subjects respectively.The coherence was tested with Pearson's correlation coefficient, the difference was tested with paired Student t testing.?RESULTS:The total correlation of the RNFL thickness, optic parameters, GCC thickness made with two kinds of OCT was between 0.7-0.8;the RNFL thickness, optic disk area etc.made with the Angio-OCT were lower than those made with FD-OCT except for the GCC thickness.?CONCLUSION: The results made with two kinds of OCT from the same subject has certain coherence, but cannot be compared directly.