亚油酸氧化产物——羟基十八碳二烯酸的研究进展

摘要

Hydroxyoctadecaenoic acids (HODEs) are oxidation products of linoleic acid (LA). Existing studies indicate that endogenous HODEs exert pathophysiological roles in the development and progression of some human diseases, while exogenous HODEs may have the same effects and the potential health risk associated with them deserves the public's concern. The present paper reviews the classification, formation mechanism, pathophysiological significance and analytical methods of HODEs. Moreover, prospects for future research in the field of food safety are also proposed.%羟基十八碳二烯酸(hydroxyoctadecaenoic acids,HODEs)是亚油酸的氧化产物,研究表明,内源性的HODEs具有病理生理学作用,与人类某些疾病的形成和发展有关;而外源性的HODEs可能具有相同的病理生理学作用,其潜在的安全隐患值得关注.本文就HODEs的种类、产生机理、病理和生理学意义、检测方法等进行综述,并就食品安全领域的相关研究作一些展望.