液相色谱-串联质谱法应用于动物源性食品中多族药物筛查确证的研究进展

摘要

为了筛查和监测动物源性食品中因不当或非法使用兽药以及一些人用药物而导致的药物残留,液相色谱-质谱联用技术成为该领域中应用最为广泛的痕量检测技术.该文从样品前处理净化方法、最新研究思路、基质效应评价、质谱检测器选取等方面对液相色谱-串联质谱法在动物源性食品中多族药物筛查确证应用的研究进展进行了综述,并对这一应用的发展前景进行了展望,希望能为相关研究的开展提供参考和启发.%In order to screen and monitor the residue of veterinary drugs and therapeutic drugs in animal processed food,high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) has become the most widely method used in the field in trace detection.The research progress of sample preparation,latest research topics,evaluation of matrix effects,and selection of the mass spectrometer were introduced.At the same time,the development prospects of this application was also discussed.This paper is to provide a reference to related research in the future.