背景：人工全膝关节置换技术在临床上已经成熟。LPS-Flex Mobile Bearing System(Zimmer，USA)人工膝假体为旋转平台高屈曲型膝关节假体，由于国内临床应用时间较短，该假体的临床应用优越性目前尚未见报道。目的：探讨应用LPS-Flex Mobile Bearing System人工膝假体(Zimmer，USA)行全膝关节置换的近期疗效，以置换后膝关节活动度及功能评价人工假体与宿主的生物相容性。方法：回顾性分析2012年2月至2014年3月苏州大学附属第一医院收治的以 Zimmer LPS-Flex Mobile Bearing System人工膝假体(高屈曲旋转平台型膝关节假体)行全膝关节置换的患者37例(42膝)，男9例(10膝),女28例(32膝)；年龄47-78岁,平均63.7岁。采用骨水泥固定，不进行髌骨置换。观察置换后并发症，比较置换前、置换后膝关节活动度，并根据纽约特种外科医院膝关节评分评估膝关节功能恢复情况。结果与结论：共34例(38膝)获得随访,随访时间6-28个月。膝关节活动度从置换前平均88.5°改善到置换后平均124.2°；置换前纽约特种外科医院膝关节评分平均为52.5分，置换后平均为91.1分，均有显著提高(P<0.01)。根据纽约特种外科医院膝关节评分系统评定疗效：优20例，良16例，中2例，优良率达95%。各种并发症的发生率低。提示高屈曲旋转平台型假体人工全膝关节置换的近期临床效果满意，该假体在设计上更具优势，更加接近膝关节生理结构，但长期效果还需进一步观察。%BACKGROUND:Total knee arthroplasty has matured in clinical treatment. LPS-Flex Mobile Bearing System (Zimmer, USA) artificial knee prosthesis is the high-flexion rotating platform type knee prosthesis. The time of its clinical application in China is short, so its advantages have not been reported. OBJECTIVE:To investigate the preliminary clinical outcome of the total knee arthroplasty with LPS-Flex Mobile Bearing system artificial knee prosthesis (Zimmer, USA), and to assess the biocompatibility of artificial prosthesis and host using range of motion of knee and function after replacement. METHODS:We retrospectively analyzed 37 patients (42 knees) undergoing total knee arthroplasty using Zimmer LPS-Flex Mobile Bearing prostheses (high-flexion rotating platform type knee prosthesis) in The First Hospital Affiliated to Soochow University from February 2012 to March 2014, including 9 males (10 knees) and 28 females (32 knees), aged 47-78 years, averagely 63.7 years. Bone cement fixation was used, and the patel a was not treated with replacement. Postoperative complications were observed. Ranges of motion of knee joint preoperatively and postoperatively were compared. The recovery of knee joint function was evaluated using Hospital for Special Surgery Knee Score. RESULTS AND CONCLUSION:A total of 34 cases (38 knees) were fol owed up for 6-28 months. Range of motion of knee joint improved from 88.5° before operation to 124.2° after operation on average. Hospital for Special Surgery Knee Score improved from 52.5 before replacement to 91.1 after replacement, showing significant differences (P<0.01). Therapeutic effects were assessed according to Hospital for Special Surgery Knee Score:excel ent in 20 cases, good in 16 cases, average in 2 cases, with an excel ent and good rate of 95%. The incidence of various complications was low. These data suggested that short-period clinical outcomes of high-flexion rotating platform type knee prosthesis replacement are satisfactory. This prosthesis has advantages in its design, which is more close to the physical structure of knee joint, but its long-period outcomes deserve further investigations.
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