运动终板药物注射治疗痉挛型脑性瘫痪的效果

摘要

目的：观察运动终板药物注射治疗痉挛型脑瘫患儿的效果。方法230例痉挛型脑瘫患儿分为对照组和观察组，每组115例。对照组给予综合康复，包括功能训练、物理因子治疗及药物应用；观察组在此基础上加痉挛肌肉运动终板注射维生素B1和维生素B12。治疗前后采用粗大运动功能测试(GMFM)评价患儿功能区的运动功能，采用改良Ashworth量表(MAS)评价痉挛程度，采用CDCC婴幼儿智能发育量表测定智力发育指数(MDI)和心理运动发育指数(PDI)。结果治疗后，两组患儿的粗大运动功能明显改善，MAS分级明显降低，MDI和PDI评分明显增加(P<0.01)；且观察组均优于对照组(P<0.05)。结论肌肉运动终板药物注射能提高脑瘫患儿粗大运动功能，减轻痉挛，改善智力发育。%Objective To explore the effect of drug injection in muscle motor points on children with spastic cerebral palsy. Methods 230 children with spastic cerebral palsy were divided into control group and observation group, with 115 cases in each group. The control group received comprehensive rehabilitation including functional training, physical therapy and medicine, while the observation group re-ceived injection of vitamin B1 and vitamin B12 in muscle motor points in addition. They were assessed with Gross Motor Function Measure (GMFM), modified Ashworth Scale (MAS), mental development index (MDI) and psychomoter developmental index (PDI) of CDCC Infant Me Ntal Development Scale. Results The gross motor function improved, MAS score decreased, the scores of MDI and PDI increased after treatment (P<0.01) in both groups, which were better in the observation group than in the control group (P<0.05). Conclusion Drug injec-tion in muscle motor points can improve the gross motor function, relieve spasm, and improve intelligence development of children with spastic cerebral palsy.