沐舒坦治疗慢性阻塞性肺病急性加重期的应用与合适剂量分析

摘要

目的：分析讨论不同剂量沐舒坦应用在慢性阻塞性肺病急性加重期患者治疗中的临床效果。方法：本组选择笔者所在医院2012年6月～2016年6月收住院的慢性阻塞性肺病急性加重期患者96例，分为48例试验组，48例对照组，对照组给予常规剂量沐舒坦治疗，实验组给予大剂量沐舒坦治疗。结果：两组总有效率比较，试验组为95.83％，对照组为77.08％，比较差异有统计学意义（P ＜0.05）。结论：大剂量沐舒坦应用在慢性阻塞性肺病急性加重期患者治疗中对于降低不良反应发生率、提高临床疗效及提高生活质量等具有着至关重要的作用。%[ABSTRACT]Objective:To analyze and discuss the clinical effect of different doses of mucosolvan in acute exacerbation of chronic obstructive pulmonary disease in the treatment of patients.Methods:In this group,June 2012 to June 2016 year in June in the author′s hospital for treatment of 96 cases of acute exacerbations of chronic obstructive pulmonary disease pa-tients as the observation object,which is divided into the control group and the experimental group according to the random number method,48 cases in each group.Among them,the control group was given conventional dose of ambroxol treat-ment,experimental group were given large doses of ambroxol treatment.Results:The total effective rate of control group was 77.08%,the total clinical rate effective was 95.83%,the clinical curative effect of the test group was significantly higher than that of the control group (P <0.05).Conclusion:Large dose of Mucosolvan in acute exacerbation of chronic obstruc-tive pulmonary disease patients to reduce the occurrence of adverse reaction rate and improve the clinical efficacy and im-prove the quality of life is very important.