磁共振特征诊断中枢神经细胞瘤

摘要

目的 探讨6种特征性MRI征象对中枢神经细胞瘤的诊断价值.方法 回顾性分析30例中枢神经细胞瘤及68例其他侧脑室肿瘤患者术前MRI,以5分法对6种MRI征象,包括扇贝征、宽基底征、皂泡征、周围泡泡征、液-液平面征及宝石征进行评分.绘制ROC曲线,评估各征象的诊断价值.结果 扇贝征曲线下面积(AUC)最大(0.82),大于其他5个征象(P均＜0.05);宽基底征、皂泡征及周围泡泡征次之(AUC为0.73～0.75),大于液-液平面征及宝石征(P均＜0.05).扇贝征特异度最高(84.56％),其次为液-液平面征(77.94％)、宝石征(74.26％)及周围泡泡征(70.34％).皂泡征敏感度最高(83.89％),其次为宽基底征(76.11％)和周围泡泡征(75.00％).结论 6种特征性MRI征象中,扇贝征对诊断中枢神经细胞瘤价值最高.%Objective To investigate the diagnostic value of six MRI characteristic features for diagnosing central neurocytoma (CN).Methods MRI data of 30 cases of CN and 68 cases of non-CN located in lateral ventricles were retrospectively analyzed.Six characteristic MRI features,including scalloping sign,broad-based attachment sign,soapbubble sign,peripheral cyst sign,fluid-fluid level sign and gemstone sign were scored based on a five-point scale.ROC curve was used to assess the diagnostic value of each MRI sign.Results The scalloping sign showed the highest area under the curve (AUC) value (0.82) among all 6 signs (all P＜0.05),followed by broad-based attachment,soap-bubble andperipheral cyst signs (AUC 0.73-0.75),higher than that of fluid-fluid level sign and gemstone sign (all P＜0.05).The scalloping sign exhibited the highest specificity (84.56 ％),followed by fluid-fluid level (77.94 ％),gemstone (74.26 ％) and peripheral cyst (70.34％) sign.The soap-bubble sign (83.89％) was the most sensitive sign,followed by broad-based attachment sign (76.11％) and peripheral cyst sign (75.00％).Conclusion The scalloping sign is the most valuable indicator for CN among six characteristic MRI features.