慢性胃肠缺血与动脉粥样硬化

摘要

慢性胃肠缺血被认为是一种较少见疾病,但随着年龄增长此病的发病率逐渐上升.动脉粥样硬化是老年人慢性胃肠缺血的最常见病因.近年来的研究显示,动脉粥样硬化性慢性胃肠缺血不仅可以导致胃肠道症状和营养不良,还明显增加心血管事件风险和心血管病死率.然而,研究也发现动脉粥样硬化性慢性胃肠缺血的危险因素、发病机制和全身动脉粥样硬化病变存在一定的差异.%Chronic gastrointestinal ischaemia( CGI) is generally considered to be a rare disease, and the incidence of CGI increases with age. Atherosclerosis is most common cause of CGI in the elderly. The results of recent study showed that atherosclerotic CGI give rise to not only abdominal symptoms and malnutrition, but also higher risks of cardiovascular events and mortality. However, the risk factors and mechanisms of atherosclerotic CGI are different to general atherosclerosis.