A new micro-scale fermentation method using microtitre plates has been developed to investigate the effects of specific hop compounds on yeast growth and metabolism. This new method is simple and reproducible, enabling the rapid examination of yeast behaviour when only small amounts of active material are available. Xanthohumol had a striking influence on yeast behaviour, prolonging the lag-phase by about a full day, but not affecting the normal growth rate. For brewers seeking to raise the concentrations of these potentially healthy compounds in their beer, we would recommend close attention to possible changes in fermentation parameters.
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