摘要：
Objective To investigate the clinical and pathological features,diagnosis,treat-ment and prognosis of cellular angiofibroma in primary epididymis,so as to facilitate the knowledges of the pathological features and diagnosis of benign tumor of epididymis. Methods One case of cel-lular angiofibroma of epididymis treated in our hospital was reported,and we searched relevant liter-ature for review and discussion. Results A complete excision of the mass was performed.Micro-scopically,the tumor realm was clear with a fiber capsule,mainly composed by the sparse spindle-shaped cells and riched in collagen and scattered in the distribution of small blood vessels.Immuno-histochemical results:SMA (vascular wall +),Caldesmon (vascular wall +),Desmin (vascular wall +),ER (spindle cell +),AR (spindle cell +),Ki-67 (-),CD34(-).The final pathological diagnosis (right scrotum tumor)was a benign tumor,in line with vascular fibroma.The patient was alive without any evidence of recurrence or metastasis after six months'follow-up. Conclusions Cellular angiofibroma is a rare epididymis tumor,occurring mainly in the genital region,and the mi-croscopic characteristics are composed of the spindle-shaped cells and thick-walled blood vessels dis-tributed in the collagen fibers of the interstitial,representing a benign mesenchymal tumor.Epididy-mis tumors are mostly benign,whose best treatment is a complete resection,and its prognosis is generally well without relapse.%目的 探讨原发性附睾富于细胞性血管纤维瘤的临床病理特征、诊治方法及预后,加强对附睾良性肿瘤病理类型和诊断的认识.方法 回顾性分析1例附睾富于细胞性血管纤维瘤的病例资料,并结合相关文献进行复习讨论.结果 患者右侧阴囊内肿物被完整切除,镜下见肿瘤境界清楚,似有纤维包膜,主要由稀疏小梭形细胞以及丰富胶原和散在分布的小血管组成.免疫组化:SMA(血管壁+),Caldesmon(血管壁+),Desmin(血管壁+),ER(梭形细胞+),AR(梭形细胞+),Ki-67(-),CD34(-).最终病理诊断为(右侧阴囊内肿物)良性肿瘤,符合血管纤维瘤.术后随访6个月,未见肿块复发.结论 富于细胞性血管纤维瘤在附睾肿瘤类型中罕见,其主要好发于两性生殖区,镜下可见梭形细胞和厚壁血管分布于富含胶原纤维的间质中,属于良性的间叶性肿瘤.附睾肿瘤大部分为良性,其治疗以手术切除为主,预后良好,一般不复发.
