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阳萎的相关文献在1983年到2022年内共计1135篇,主要集中在外科学、中国医学、内科学 等领域,其中期刊论文1067篇、会议论文14篇、专利文献54篇;相关期刊401种,包括河北中医、陕西中医、上海针灸杂志等; 相关会议14种,包括中国民族医药学会疑难病分会2014年学术交流会、第一次全国中西医结合男科青年学术会议暨四川省第三届中西医结合男科学术年会、第十四届全国临床医学影像学术会议等;阳萎的相关文献由1811位作者贡献,包括胡礼泉、张思孝、杨罗艳等。

阳萎—发文量

期刊论文>

论文:1067 占比:94.01%

会议论文>

论文:14 占比:1.23%

专利文献>

论文:54 占比:4.76%

总计:1135篇

阳萎—发文趋势图

阳萎

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  • 胡礼泉
  • 张思孝
  • 杨罗艳
  • 郑新民
  • 颜怀伟
  • 颜怀玮
  • 姚德鸿
  • 梅骅
  • 薛兆英
  • 期刊论文
  • 会议论文
  • 专利文献

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    • 吴宗传; 李俊杰; 胡开理; 席俊羽; 戴宁
    • 摘要: 目的观察补肾疏肝兴阳汤联合他达拉非片对动脉性勃起功能障碍(ED)肝郁肾虚型患者勃起功能和阴茎海绵体动脉血流动力学的影响。方法将70例动脉性ED肝郁肾虚型患者按照随机数字表法分为2组,治疗组35例(脱落5例)予补肾疏肝兴阳汤联合他达拉非片治疗,对照组35例(脱落4例)单纯应用他达拉非片治疗,2组均治疗12周,疗程结束后随访8周。比较2组治疗前后国际勃起功能问卷-5(IIEF-5)评分;比较2组治疗前后阴茎海绵体动脉血流动力学指标收缩期峰值流速(PSV)、舒张末期流速(EDV)及阻力指数(RI)变化;比较2组治疗后、随访时性活动日志问题4(SEP4)、SEP5满意度;观察2组安全性情况。结果2组治疗后IIEF-5评分均较本组治疗前升高(P<0.05),且治疗组升高更明显(P<0.05)。治疗组治疗后PSV、EDV、RI均较本组治疗前升高(P<0.05),对照组治疗后PSV、EDV均较本组治疗前升高(P<0.05),且治疗组治疗后PSV、EDV、RI均高于对照组(P<0.05)。治疗后、随访时治疗组SEP4、SEP5满意度均高于对照组(P<0.05)。2组患者均无明显不良反应。结论补肾疏肝兴阳汤联合他达拉非片能改善动脉性ED肝郁肾虚型患者勃起功能,提高性自信及性自然性,从而改善性生活质量,近期疗效、远期疗效均优于单纯应用他达拉非片治疗。
    • 逯雪峰; 杨华睿; 张曈; 童明辉
    • 摘要: 目的:分析不同阴茎勃起功能障碍(Erectile dysfunction,ED)患者颈总动脉管壁硬度的变化.方法:收集2019年1-12月因ED前来泌尿外科就诊的患者185例,排除30例患有糖尿病、高血压、动脉粥样硬化斑块等影响血管壁硬度疾病的患者,最后155例纳入研究,根据注射药物后阴茎背动脉血流参数对受试者进行分类.结果:所有受试者年龄,左、右侧颈总动脉脉搏波传导速度(Pulse wave velocity,PWV)、剪切波弹性成像技术(Shear wave elastography,SWE)值无明显差异,前壁SWEmean值大于后壁且有统计学意义(P<0.05);动脉性ED患者颈总动脉PWV及SWE平均值均较静脉性ED及非血管性ED增大;静脉性ED与非血管性ED间均无统计学差异(P>0.05).结论:动脉性ED与心血管疾病之间关系密切,利用PWV与SWE技术证明动脉性ED患者颈总动脉管壁硬度较静脉性ED及非血管性ED患者大.
    • 李松林
    • 摘要: 从精气神定义、精气神互化、天人相应、调神、节精、药补、食补等方面,论述精气神学说在男性房事养生中的哲学意义。由于气和精能充养神,神能反作用于精和气。气和精之亏损可赖食补,药补,调神则靠挖掘传统的修性养神的知识去实现,达到精神稳定而快乐的健康状态。气和神不能化精固精会出现阳萎,反之,性寿命延长。本文强调性幸福与长寿的统一性及具体调理方法。
    • 刘凤霞; 毛吾兰·买买提依明; 阿卜杜热伊木江·如则; 朱彦刘莹; 张盼盼; 阿地力江·伊明
    • 摘要: Obstract To study the roles of Yimusake on SP and AchE expressions in penis tissue of abnormal phlegmatic syndrome with impotence disease rats model.Methods A total of 100 mature male Sprague-Dawley rats were randomly divided into two groups.Rats in model group (n =90) were treated with cold-wet environment and diet,and rats (n =10) in normal control group with normal environment and diet.Biological parameters and sexual behavior of the rats were observed for 20 weeks until establishment of abnormal phlegmatic syndrome rat model.Through APO erection test,we selected impotence rat model,the rats were randomly divided into 3 groups (A1,A2,A3) and disproved for 2 weeks.The expressions of SP and AchE were detected by immunohistochemistry.Results (1)SP expression in A1、A2、A3 groups were increased compared with that in N group (P<0.05);SP expression in A3 group was decreased compared with that in A1、A2 group (P<0.05).(2) AchE expression in A1、A2 groups were decreased compared with that in N group(P<0.05);Ache expression in A3 group was increased compared with that in A1 group (P<0.05).Conclusion Higher expression of SP and lower expression AchE occurred in penis tissue of abnormal phlegmatic syndrome with impotence disease rat model.Yimusake might play key roles in treatment of abnormal phlegmatic syndrome with impotence disease rat model via regulating the SP and AchE expression.%目的 研究异常黏液质型阳痿病证大鼠模型阴茎组织中P物质(SP)、乙酰胆碱酯酶(AchE)的表达与伊木萨克片的影响,探讨其生物学意义.方法 取100只正常雄性SD大鼠,随机取10只作为正常对照组(N),余90只是造模组,采用湿寒环境和饮食方法建立异常黏液质证候大鼠模型,根据勃起和交配实验,筛选出44只阳痿病证大鼠模型,并将其随机分为病证模型组(A1)、病证自然反证组(A2)、病证药物反证组(A3).反证后,免疫组化方法检测阴茎组织中SP、AchE的表达.结果 (1)大鼠阴茎组织中SP表达:A1、A2和A3组较N组显著增高(P<0.05);A3组较A1、A2组显著降低(P<0.05). (2)大鼠阴茎组织中AchE表达:A1、A2组较N组显著降低(P<0.05);A3组较A1组显著升高(P<0.05).结论 异常黏液质型阳痿病证大鼠模型阴茎组织中SP显著增高、AchE显著降低,对证维药伊木萨克片可能通过下调SP、上调AchE表达对异常黏液质型阳痿病证大鼠模型发挥作用.
    • 王铮
    • 摘要: 目的:研究彩色多普勒超声联合药物注射及刺激结合试验(CIS)在阴茎勃起功能障碍(ED)诊断中的应用价值.方法:对285例临床诊断ED患者进行海绵体注射前列地尔10 μg,观察双侧阴茎海绵体动脉的血流动力学变化.结果:非血管性ED 186例(65.2%),动脉性ED 15例(5.3%),静脉性ED 66例(23.2%),混合性ED 18例(6.3%).结论:彩色多普勒超声血流显像结合CIS试验是诊断血管性ED的可靠检查方法,并可以对血管性ED加以分型,为临床治疗提供有价值的依据.
    • 刘凤霞; 腊博雅; 刘琪; 艾热提·吾杰克; 热西旦·亚力坤; 彭世宇; 张盼盼; 马文静; 阿地力江·伊明
    • 摘要: 目的:研究RhoA、Rho激酶(ROCK1)在异常黏液质证候及阳痿病证大鼠模型阴茎组织中的表达,并探讨维药伊木萨克片干预后对其表达的影响。方法选用50只性功能正常的雄性SD大鼠,其中10只为正常对照组(N组),余40只为造模组,采用湿寒饲料+湿寒环境的干预条件建立异常黏液质证候模型大鼠,20周筛选出阳痿病证模型大鼠,并将其分为病证模型组(A1)和病证药物反证组(A3);未成阳痿的大鼠分为证候模型组(B1),证候药物反证组(B3)。伊木萨克片反证2周后,免疫组化和Western -blot方法检测各组大鼠阴茎组织中RhoA、ROCK1的表达。结果 A1、A3、B1组大鼠阴茎组织中RhoA、ROCK1表达均高于N组(P<0.05)。A3组大鼠阴茎组织中RhoA、ROCK1表达均低于A1组(P<0.05)。B3组大鼠阴茎组织中RhoA、ROCK1表达明显低于B1组(P<0.05)。结论 RhoA/ROCK1信号系统可以促进大鼠异常黏液质证候及阳痿病证的发生,伊木萨克片可能通过抑制RhoA/ROCK1信号通路对异常黏液质证候及阳痿病证大鼠模型发挥治疗作用。%Objective To study the expression of RhoA/Rho-kinase in penis tussue of rat model with abnormal phlegmatic syndrome and impotence disease and intervention effect of Yimusake on it.Methods Total of 50 normal mature male SD rats were used in the study, and 10 of them were randomly chosen as the normal control group (N group), other 40 were treated with spinach and coriander diet in a cold and humid environment to have abnormal phlegmatic syndrome and impotence disease. The established rat models were randomly divided into abnormal phlegmatic syndrome group (B1), medication disproof group of abnormal phlegmatic syndrome (B3), impotence model group (A1), medication disproof group of impotence model (A3). After 2 weeks Yimusake treatment, we measured the expression of RhoA/Rho-kinase in penis tissues of different groups.Results The results showed that RhoA, ROCK1 expressions in A1, A3, B1 group were higher than that in N group (P<0.05). RhoA and ROCK1 expressions in A3 group were lower than that in A1 group (P<0.05). RhoA and ROCK1 expressions in B3 group were lower than that in B1 group (P<0.05).Conclusion RhoA/Rho kinase signaling system can contribute to the development of abnormal phlegmatic syndrome and impotence disease. Yimusake may have a therapeutic role for abnormal phlegmatic syndrome and impotence disease through inhibiting RhoA/Rho kinase signaling pathways.
    • 马文静; 毛吾兰•买买提依明; 张盼盼; 斯依提•阿木提; 刘凤霞; 薛志琴; 蒋萍; 阿莱•巴合提汗; 阿地力江•伊明
    • 摘要: 目的 应用iTRAQ标记技术结合IPA生物分析平台,筛选异常黏液质型阳痿病证特异性差异表达蛋白候选标志物,并探讨其分子机制.方法 建立异常黏液质证候模型,并筛选阳痿病证模型后,分为正常组(N)、证候组(B1)和病证组(A1)共3组(n=10),分离血清,进行iTRAQ标记结合LC-MS-MS蛋白质组学分析,应用IPA在线生物平台对异常黏液质型阳痿病证组大鼠血清差异表达蛋白进行蛋白质调控网络分析、生物功能分析、典型通路分析和生物标志物筛查分析.结果 通过蛋白质组学技术获得61种异常黏液质型阳痿病证血清差异蛋白,IPA分析结果为,候选差异表达蛋白质中6种与血管内皮功能相关;3种与平滑肌活动相关;10种与炎症相关.参与的主要生物学过程为损伤反应、炎症反应和防御反应等,涉及的主要通路为LXR/RXR通路和FXR/RXR通路等,并获得与勃起功能障碍疾病相关的标志物4个,分别是C反应蛋白、血管紧张素原、T-激肽原1以及β-2-糖蛋白1.结论 炎症和血管内皮功能改变可能在该病证发生发展中发挥着关键性作用,上述4种蛋白可能可以作为异常黏液质型阳痿病证大鼠与勃起功能障碍疾病相关的血清候选差异蛋白.%Objective To screen the candidate serum biomarkers for abnormal phlegmatic syndrome with impotence disease using iTRAQ and IPA bioanalysis platform, and explore its molecular mechanism.Methods Rats with abnormal phlegmatic syndrome model were established, and abnormal phlegmatic syndrome rats model with impotence were selected and divided into three groups: the control group(N), phlegmatic syndrome model group(B1) and phlegmatic syndrome model group with impotence (A1) (n=10). Serum proteomics of these rats among three groups were comparatively analyzed by iTRAQ labeling combined with LC-MS-MS. Differentially expressed serum proteins were further analyzed by IPA online bioinformatics software,including networks analysis, biofunction Analysis, canonical Pathways and IPA Biomarker~Filter analysis.Results Total of 61 differentially expressed serum proteins were identified by iTRAQ. IPA bioanalysis showed that 6 different proteins were associated with vascular endothelial function, 3 proteins of smooth muscle activity,10 proteins associated with inflammation. The main biological processes of differential proteins were injury, inflammation reaction and defense response. The pathways involved in LXR/RXR activation and FXR/RXR activation. Four candidate biomarkers associated with Erectile Dysfunction disease were found, including C-reactive protein, Angiotensinogen, T-kininogen-1 andβ-2-glycoprotein 1.Conclusion Inflammation and vascular endothelial function may play a key role in the development of this disease, four proteins can be used as candidate proteins related to abnormal phlegmatic with impotence disease.
    • 耿琦; 崔晨; 李敬伟; 胡琪祥; 李威; 蒋健
    • 摘要: 目前中医临床治疗阳萎多从补肾入手,但未必皆效.蒋健教授根据多年临床经验总结发现,阳萎非惟肾虚,亦关肝脉;治疗非惟补肾,亦需治肝,甚至必要时以治肝为主.本文结合古代文献、现代药理以及临床验案分析,介绍蒋健教授临证肝肾同治,以肝为主治疗阳萎的观点.
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