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Compositions and methods of use for a major outer capsid protein (VP7) of rotavirus SA-11
Compositions and methods of use for a major outer capsid protein (VP7) of rotavirus SA-11
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机译:轮状病毒SA-11的主要外衣壳蛋白(VP7)的成分和使用方法
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摘要
The gene coding for SA-11 rotavirus major outer capsid protein (VP7) was cloned and expressed in a baculovirus-insect cell expression system. The protein, which is antigenically similarto native VP7 protein, has a molecular weight of 34 kilodaltons and is secreted into the tissue culture media. The recombinant VP7 protein is reactive with neutralizing antiserum prepared against SA-11 virus and can be utilized in a vaccine, as an antigenic preparation for producing antibodies or in a diagnostic assay.
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