Novel fluorinated or hydroxylated phenylimidazolidines having anti-androgenic activity, method for preparing same, resulting intermediates, and pharmaceutical compositions

摘要

PCT No. PCT/FR96/01846 Sec. 371 Date Jun. 23, 1998 Sec. 102(e) Date Jun. 23, 1998 PCT Filed Nov. 21, 1996 PCT Pub. No. WO97/19064 PCT Pub. Date May 29, 1997A particular subject of the invention is the products of formula (I): in which: R1 and R2 represent in particular cyano and trifluoromethyl, R3 represents in particular alkyl, alkenyl or alkynyl, optionally substituted by one or more halogen, cyano or hydroxyl radicals, R4 and R5 either represent in particular methyl optionally substituted by fluorine, or form in particular a cyclohexyl radical, X and Y represent in particular oxygen, as well as their salts and isomers.