NOVEL CRYSTALLINE FORMS OF (S)-N-(1-CARBOXY-2-METHYL-PROP-1-YL)-N-PENTANOYL-N-2'-(1H-TETRAZOL-5-YL)BI-PHENYL-4-YLMETHYL-AMINE

摘要

Disclosed herein is novel crystalline forms of Valsartan namely, a crystalline form designated as Form A, and its solvates thereof, novel crystalline form of Valsartan designated as Form B and solvates thereof, novel crystalline form of Valsartan designated as Form C and solvates thereof, novel crystalline form of Valsartan designated as Form D and its solvates thereof, processes for their preparation, pharmaceutical compositions containing these polymorphs and their use in medicine. The present invention further discloses a novel process for preparing a stable amorphous form of Valsartan and in this connection to amorphous form of Valsartan produced by such processes. The present invention also discloses a novel process for obtaining stable Form I crystals of Valsartan.