PROCESSES FOR PREPARING ORGANOLEPTICALLY ACCEPTABLE INTRAORALLY DISINTEGRATING COMPOSITIONS

摘要

a step of providing an organoleptically valdecoxid in particulate form; a step of adding to the drug at least one pharmaceutically acceptable dissolution retardant to form a drug composite; a step of admixing with the drug composite at least one pharmaceutically acceptable excipient that exhibits rapid oral dissolution, said admixing step forming a tableting blend; a step of granulating the drug, drug composite, or tableting blend; and a step of compressing the tableting blend to form the fast-melt composition; wherein said granulating step occurs prior to, simultaneously with, and/or after said step of adding the dissolution retardant.