A nanoimprint lithography device includes a base, a pair of opposite rotator formed on the base, and a printing mold connected to the rotators. The printing mold includes a cylindrical main body having a nanometer-scale pattern formed thereon and a pair of connecting piece detachably connected to the main body. The printing mold is connected to the rotators via the connecting pieces and is configured to be driven by the rotators to print the nanometer-scale pattern on a substrate.
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