COMPOUNDS FOR APPLICATION IN VISUALISATION, DIAGNOSTICS AND/OR TREATMENT OF CENTRAL NERVOUS SYSTEM DISEASES OR TUMOURS

摘要

FIELD: chemistry.;SUBSTANCE: invention relates to compound of formula Ia , where W represents -C(U¹)(U²)-C=CH, U¹ and U², which are independently selected from hydrogen; A is selected from group, containing non-substituted phenyl, non-substituted heteroaryl, the same as furanyl, G¹, G² and G³ in formula Ia are independently and separately, in each case, selected from group, containing hydrogen, (C₁-C₄)alkyl, preferably methyl, L and (C₁-C₆)alkyl-L, on condition that it is one of G¹-G³ in formula Ia that is selected from L and (C₁-C₆)alkyl-L, and L represents methylsulfonyloxy group, or L represents F, preferably ¹⁸F, n=0, m=0, and to its pharmaceutically acceptable salt. Invention also relates to methods of claimed compound obtaining, compositions, which contain such compounds, for treatment and/or diagnostics and/or visualisation of central nervous system diseases or tumours.;EFFECT: obtained are novel compounds and based on them compositions, which can be applied in medicine for diagnostic visualisation by means of positron-emission tomography.;26 cl, 15 dwg, 8 ex