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West Nile virus structural protein-specific monoclonal antibody, and method for determining West Nile virus infection using the monoclonal antibody

机译:西尼罗河病毒结构蛋白特异性单克隆抗体,以及使用该单克隆抗体确定西尼罗河病毒感染的方法

摘要

The invention addresses the problem of providing a method capable of determining infection with West Nile virus (WNV) rapidly and with high accuracy. According to the invention, a monoclonal antibody which specifically recognizes an envelope protein (E) or a pre-membrane protein (PrM), which is a structural protein of West Nile virus (WNV) and a method for determining WNV infection by competitive ELISA in which the monoclonal antibody and a test serum are simultaneously added to a solid phase are provided.
机译:本发明解决了提供能够快速且高精度地确定西尼罗河病毒(WNV)感染的方法的问题。根据本发明,一种特异性识别作为西尼罗河病毒(WNV)的结构蛋白的包膜蛋白(E)或前膜蛋白(PrM)的单克隆抗体,以及通过竞争性ELISA确定WNV感染的方法。提供了将单克隆抗体和测试血清同时加入固相的方法。

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