首页> 外国专利> IMMUNOGENIC BACTERIAL PROTEINS, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME, AND VACCINES AGAINST SHIGA-TOXIN-PRODUCING ESCHERICHIA COLI

IMMUNOGENIC BACTERIAL PROTEINS, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME, AND VACCINES AGAINST SHIGA-TOXIN-PRODUCING ESCHERICHIA COLI

机译：免疫原性细菌蛋白，包含相同成分的药物组合物和抗产志贺毒素的大肠杆菌的疫苗

展开▼

页面导航

摘要

著录项

相似文献

摘要

There are different strains of Shiga toxin-producing Escherichia coli (STEC),associated with foodborne diseases, which can produce hemolytic uremic syndrome (HUS). The invention corresponds to antigens as vaccines, which are recognised by the serum of patients with SUH and recognised both by IgG and IgA. 展开▼

机译：产生志贺毒素的大肠埃希氏菌（STEC）和食源性疾病有不同的菌株，它们可产生溶血性尿毒症综合征（HUS）。本发明对应于作为疫苗的抗原，其被SUH患者的血清识别并被IgG和IgA识别。展开▼

著录项

公开/公告号WO2015164989A1

专利类型

公开/公告日2015-11-05

原文格式PDF

申请/专利权人 UNIVERSIDAD DE CHILE;
展开▼

申请/专利号WO2015CL00026

发明设计人 MONTERO FORERO DAVID ARTURO;DEL CANTO FUENTES FELIPE ANTONIO;SALAZAR GARRIDO JUAN CARLOS;VIDAL ALVAREZ ROBERTO MAURICIO;
展开▼

申请日2015-04-24

分类号A61K39/108;A61P31/04;

国家 WO

入库时间 2022-08-21 15:03:21

相似文献

专利

外文文献

中文文献

1. 新型产志贺毒素F18型大肠杆菌噬菌体Esc-COP-1及其用于抑制产志贺毒素F18型大肠杆菌增殖的用途 [P] . 中国专利： CN107208068B . 2021.04.20

2. 新型产志贺毒素F18型大肠杆菌噬菌体Esc‑COP‑1及其用于抑制产志贺毒素F18型大肠杆菌增殖的用途 [P] . 中国专利： CN107208068A . 2017-09-26

3. Pharmaceutical composition useful as a Vaccine against bacteria producing Escherichia coli (STEC) shigatoxinas, comprising at least one Outer Membrane Protein Antigen or an immunogenic immunogenic Protein Associated and preserved in STEC strains. [P] . CL2014001126A1 . 2014-08-29

机译：用作抗产大肠杆菌（STEC）志贺毒素的细菌的疫苗的药物组合物，其包含至少一种与STEC菌株相关并保存的外膜蛋白抗原或免疫原性免疫原蛋白。

4. Immunogenic composition, composition isolated immunogenic, vaccine, method of treatment or prevention of gram negative bacterial disease, the use of the vaccine.Gram negative bacterial strain genetically manipulated, method for preparing immunogenic composition, method to prepare the vaccine.Method of preparing an immunoglobulin for use in the prevention or treatment of infection neisserial, preparation of immunoglobulin, pharmaceutical preparation and use of pharmaceutical preparation. [P] . BR0313100A . 2005-06-21

机译：免疫原性组合物，分离的具有免疫原性的组合物，疫苗，治疗或预防革兰氏阴性细菌疾病的方法，疫苗的使用。基因操作的革兰氏阴性细菌菌株，制备免疫原性组合物的方法，制备疫苗的方法。免疫球蛋白的制备方法用于预防或治疗奈瑟氏菌感染，免疫球蛋白的制备，药物制剂和药物制剂的用途。

5. METHOD OF HIGH-LEVEL EXPRESSION, METHOD OF PURIFICATION AND METHOD OF OVER-STACKING OF PORINE PROTEIN OF MENINGOCOCCUS OF GROUP B EXTERNAL MEMBRANE OR PROTEIN FUSED WITH ITS, HIGHLY PURIFIED PORINE PROTEIN (VARIANTS), HIGHLY PURIFIED FUSED PROTEIN (VARIANTS), VACCINE FOR PROPHYLAXIS OF BACTERIAL MENINGITIDIS OF GROUP B, METHOD OF PREPARING CONJUGATE OF MENINGOCOCCUS OF GROUP B PROTEIN AND POLYSACCHARIDE, METHOD OF PROPHYLAXIS OF BACTERIAL MENINGITIDIS, STRAIN OF ESCHERICHIA COLI (VARIANTS) [P] . 俄罗斯专利： RU2181378C2 . 2002-04-20

机译：高蛋白表达（变种），高纯度蛋白（变种）融合的B族外膜或蛋白的脑膜炎球菌的高表达方法，纯化方法和猪粪蛋白超标方法B组细菌性肠球菌的原发性，B组蛋白与多糖的球菌的共轭的制备方法，细菌性肠球菌的原发性，大肠埃希氏菌属（变种）

1. Modification in Media Composition to Obtain Secretory Production of STxB-based Vaccines using Escherichia coli [J] . Mohammad Sadraeian, Mohammad Bagher Ghoshoon, Milad Mohkam, 中国病毒学：英文版 . 2013,第001期

2. Immunogenicity and protective efficacy of DHBV DNA vaccines expressing envelope and capsid fusion proteins in ducks delivered by attenuated Salmonella typhimurium [J] . LIU Si-yang123, JIA Ren-yong123, LI Qing-qing123, 农业科学学报：英文版 . 2018,第004期

3. Immunogenicity and protective efficacy of DHBV DNA vaccines expressing envelope and capsid fusion proteins in ducks delivered by attenuated Salmonella typhimurium [J] . LIU Si-yang, LIU Ma-feng, ZHAO Xin-xin, 农业科学学报（英文版） . 2018,第004期

4. Immunogenicity of Rcombinant Type 1 Pilus Oil-emulsified Vaccine of Avian Escherichia coil in Chickens [J] . GAN Li-ming, JIANG Jia-jin, ZHANG Miao, 动物与饲料科学：英文版 . 2012,第001期

5. Towards a vaccine for attaching/effacing Escherichia coli: a LEE encoded regulator (ler) mutant of rabbit enteropathogenic Escherichia coli is attenuated, immunogenic, and protects rabbits from lethal challenge with the wild-type virulent strain [J] . Zhu C, Feng S, Thate TE, Vaccine . 2006,第18期

6. Immunogenicity of EIT chimeric protein expressed in transplastomic tobacco plants towards development of an oral vaccine against Escherichia coli O157:H7 [J] . Farrokh Karimi, Amir Mousavi, Ali Hatef Salmanian, Plant Biotechnology Reports . 2013,第4期

7. Clinical trial to evaluate safety and immunogenicity of an oral inactivated enterotoxigenic Escherichia coli prototype vaccine containing CFA/I overexpressing bacteria and recombinantly produced LTB/CTB hybrid protein [J] . Lundgren A., Leach S., Tobias J., Vaccine . 2013,第8期

8. Bacterial protein acetylation in response to carbon overflow: quantifying changes in acetylation status of Escherichia coli metabolic networks by label-free proteomics [C] . Birgit Schilling, D. Christensen, D.J. Sorensen, ASMS Conference on Mass Spectrometry and Allied Topics . 2015

9. Recombinant vaccines against infectious hematopoietic necrosis virus: Bacterial systems for vaccine production and delivery (Oncorhynchus mykiss, Caulobacter crescentus, Escherichia coli, Yersinia ruckeri). [D] . Simon, Benjamin E. 2002

10. Purification Characterization and Immunogenicity of a Disulfide Cross-Linked Plasmodium vivax Vaccine Candidate Antigen Merozoite Surface Protein 1 Expressed in Escherichia coli [O] . Sheetij Dutta, Lisa A. Ware, Arnoldo Barbosa, 2001

11. Immunogenicity and protective efficacy of a single-dose live non-pathogenic Escherichia coli oral vaccine against F4-positive enterotoxigenic Escherichia coli challenge in pigs [O] . Fairbrother John Morris, Nadeau Éric, Bélanger Louise, 2017

12. Immunologic Control of Diarrheal Disease due to Enterotoxigenic Escherichia coli: Reactogenicity, Immunogenicity, and Efficacy Studies of Purified Escherichia coli H10407 Type 1 Somatic Pili Vaccine. [R] . Levine, M. M., Black, R. E., Clements, M. L. 1980

1. Modification in Media Composition to Obtain Secretory Production of STxB-based Vaccines using Escherichia coli [J] . Mohammad Sadraeian ,Mohammad Bagher Ghoshoon ,Milad Mohkam . 中国病毒学 . 2013,第001期

2. 产志贺毒素大肠杆菌毒素基因的敲除 [C] . 潘虹 ,朱善元 ,成大荣 . 2012年中国畜牧兽医学会兽医病理学分会暨中国病理生理学会动物病理生理专业委员会学术研讨会 . 2012

3. 产肠毒素性大肠杆菌ST-LTB融合蛋白不同佐剂纳米疫苗的筛选及其免疫原性研究 [A] . 简敏捷 . 2011