METHOD OF EVALUATING THE EFFECTIVENESS OF ANTI-TUBERCULOSIS THERAPY IN PATIENTS WITH GENITAL TUBERCULOSIS

摘要

FIELD: medicine.;SUBSTANCE: invention relates to medicine and is a method of evaluating the effectiveness of therapy of genital tuberculosis comprising control Immunoassays, characterized in that at the end of the initial phase of therapy is carried out 1^st control, which comprises determining the stimulation index of interferon-gamma (IFN-γ) with purified tuberculin (PPD-L), the definition of the levels of specific immunoglobulins (IgA, IgM) for mycobacterium tuberculosis (MBT) by enzyme-linked immunosorbent assay (ELISA), and the 2^nd control is carried out through the 6-11 months after the end of the main course of therapy, In the case when a stimulation index IFNγ with PPD-L at the end of the intensive phase of TB treatment was higher than 7, 8 - only IFNγ with PPD-A, if the optical density IgM to MBT has a 0.600 - only IgM to MBT, when the optical density at MBT to IgA was more than 0.450 - control is performed only to IgA; while the results of controlled studies recommend an extension or correction, or the end of therapy.;EFFECT: invention provides a more accurate assessment of TB therapy.;1 cl, 2 ex, 1 tbl