A CMOS device comprises a substrate with a plurality of regions, the regions including an N-type region and a P-type region which meet each other in a PN-boundary, two or more P-type active regions embedded in the N-type region, and two or more N-type active regions embedded in the P-type region. The PN-boundary or a section of the PN-boundary is a chain of line segments. Any two adjoining line segments of the chain are angled relative to each other at their connecting point. The CMOS device can be designed using abutting standard cells.;For each of two or more operating points, rise delays and fall delays associated with one or more clock cells are estimated. If the estimated rise delays and fall delays satisfy a given set of constraints, the layout of the CMOS device is accepted. Otherwise the layout is updated and a new analysis round is performed.
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