首页> 外国专利> METHOD FOR PREDICTING EFFECT OF DAIKENCHUTO AND METHOD FOR DETERMINING DOSAGE OF DAIKENCHUTO

METHOD FOR PREDICTING EFFECT OF DAIKENCHUTO AND METHOD FOR DETERMINING DOSAGE OF DAIKENCHUTO

机译:预测大池虫效果的方法和确定大池虫剂量的方法

摘要

Provided are a method for predicting the effect of Daikenchuto, a method for determining the dosage of Daikenchuto, etc. using an objective index by a method for predicting the effectiveness of Daikenchuto in a patient characterized by including the following steps (a) and (b): (a) a step of determining the ratio of the phylum Bacteroidetes to the phylum Firmicutes (Bm/Fm ratio) in the intestine of the patient by analyzing the intestinal flora of the patient; and (b) a step of determining the effectiveness of Daikenchuto in the patient by comparison with criteria such that when the Bm/Fm ratio is lower than a reference value, Daikenchuto is more effective, and when the Bm/Fm ratio is higher than a reference value, Daikenchuto is less effective, and a method for determining the dosage of Daikenchuto for a patient characterized by including the following steps (a) and (e): (a) a step of determining the ratio of the phylum Bacteroidetes to the phylum Firmicutes (Bm/Fm ratio) in the intestine of the patient by analyzing the intestinal flora of the patient, and (e) a step of determining the dosage of Daikenchuto for the patient by decreasing the dosage of Daikenchuto for the patient when the Bm/Fm ratio determined in the step (a) is a lower value than a reference value, and increasing the dosage of Daikenchuto for the patient when the Bm/Fm ratio is a higher value than a reference value.
机译:本发明提供一种通过预测以下的步骤(a),(b)为特征的患者中的预测效果的方法,使用客观指标来预测代金中毒的效果的方法,确定代金中毒的剂量的方法等。 ):(a)通过分析患者肠道中的拟杆菌门与坚定门的比率(B m / F m 比率)的步骤患者的肠道菌群; (b)通过与B m / F m 之比低于参考值的标准进行比较来确定Daikenchuto对患者的有效性的步骤, Daikenchuto效果更好,当B m / F m 比值大于参考值时,Daikenchuto效果较差,并且确定了Daikenchuto剂量的方法其特征在于包括以下步骤(a)和(e)的患者:(a)确定拟杆菌门与刚菌门(B m / F m <通过分析患者的肠道菌群在患者肠道中的/ Sub>比率,以及(e)通过在B 时减少患者的Daikenchuto剂量来确定患者的Daikenchuto剂量的步骤步骤(a)中确定的m / F m 比值低于参考值,并且当B m / F m ratio是比参考值高的值。

著录项

  • 公开/公告号EP3438273A1

    专利类型

  • 公开/公告日2019-02-06

    原文格式PDF

  • 申请/专利权人 TSUMURA & CO.;

    申请/专利号EP20170774327

  • 发明设计人 NISHIYAMA MITSUE;

    申请日2017-03-15

  • 分类号C12Q1/02;C12Q1/68;G01N33/48;C12N1/20;

  • 国家 EP

  • 入库时间 2022-08-21 12:25:45

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