virus-like particle, nucleic acid construct, vector, host cell, plant or plant tissue, seed or progeny of the plant or plant tissue, composition, methods for isolating and purifying target charged molecule and for protecting target molecule against hydrolysis and process for purifying similar particles and viruses

摘要

virus-like particle, nucleic acid construct, vector, host cell, plant or plant tissue, plant or plant seed or progeny, composition, methods for isolating and purifying the target charged molecule and for protecting target molecule against hydrolysis and process for purifying Virus-like Particles The present invention relates to novel processes and compositions that use hydrolysis-resistant viral capsid proteins to prepare virus-like particles to enclose and later isolate and purify charged molecules of interest, including nucleic acids, such as sirnas and shrna's, and small peptides.