The particle similar to a virus, nucleic acid construct, vector, host cell, plant or vegetable tissue, seed or the offspring of the plant or vegetable tissue, composition.Methods to isolate and purify the target molecule and target molecule loaded to protect against hydrolysis and process for purifying virus particles and similar

摘要

Novel processes and compositions are described which use viral capsid proteins resistant to hydrolases to prepare virus-like particles to enclose and subsequently isolate and purify target cargo molecules of interest including nucleic acids such as siRNA's and shRNA's, and small peptides.