The present invention is related to a nucleic acid molecule capable of binding to human C5a, wherein the nucleic acid molecule comprises a central stretch of nucleotides, wherein the central stretch of nucleotides comprises a nucleotide sequence of 5' AUGn1GGUGKUn2n3RGGGHUGUKGGGn4Gn5CGACGCA 3' [SEQ ID NO: 61], wherein n1 is U or dU, n2 is G or dG, n3 is A or dA, n4 is U or dU, n5 is U or dU and G, A, U, C, H, K, and R are ribonucleotides, and dU, dG and dA are 2'-deoxyribonucleotides.
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机译：本发明涉及能够与人C5a结合的核酸分子，其中该核酸分子包含中央核苷酸区段，其中该中央核苷酸区段包含5'AUGn1GGUGKUn2n3RGGGHUGUKGGGn4Gn5CGACGCA 3'的核苷酸序列[SEQ ID NO： 61]，其中n1是U或dU，n2是G或dG，n3是A或dA，n4是U或dU，n5是U或dU，并且G，A，U，C，H，K和R是核糖核苷酸，并且dU，dG和dA是2'-脱氧核糖核苷酸。
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