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SYSTEM AND METHOD FOR HIGH-THROUGHPUT RADIO THIN LAYER CHROMATOGRAPHY ANALYSIS

机译:高通量无线电薄层色谱分析系统和方法

摘要

A method of performing high-throughput radio thin layer chromatography (radio-TLC) includes spotting a plurality of locations on one or more TLC plates with samples containing a radiochemical or a radiopharmaceutical, each location defining an individual lane on the one or more TLC plates for the respective samples. The one or more TLC plates are developed with a developing solution and dried. The TLC plates are imaged with an imaging device comprising a camera, wherein the image obtained from the camera comprises a field of view that contains regions of interest (ROIs) from the plurality of lanes. The ROIs in the images obtained from the camera may then be analyzed by the user. The ROIs may be used, for example, reaction optimization or for quality control check of the production of radiotracers.
机译:一种执行高通量放射性薄层色谱法(radio-TLC)的方法,包括在一个或多个TLC板上的多个位置上都标有含有放射化学或放射性药物的样品,每个位置在一个或多个TLC板上定义了一条泳道对于各个样品。用显影溶液将一个或多个TLC板显影并干燥。用包括照相机的成像装置对TLC板成像,其中从照相机获得的图像包括视野,该视野包含来自多个车道的感兴趣区域(ROI)。然后,用户可以分析从相机获得的图像中的ROI。 ROI可以用于例如反应优化或放射性示踪剂生产的质量控制检查。

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