- DRUG-LAYERED SILICATE COMPOSITE FOR ENHANCED ORAL BIOAVAILABILITY ORAL PHARMACOLOGICAL COMPOSITION INCLUDING THE DRUG-LAYERED SILICATE COMPOSITE AND METHOD OF MANUFACTURING THE DRUG-LAYERED SILICATE COMPOSITE

摘要

Drug-layered silicate complexes are disclosed. The drug-layered silicate complex includes a layered silicate powder and a sorafenib drug compound bound between layers of the silicate powder and present in an amorphous state. When using such a complex, it is possible to significantly improve the absorption and bioavailability in the body than the existing sorafenib compound.