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一种依度沙班冻干口崩片及其制备方法

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摘要

本发明属于药物制剂领域，具体涉及一种依度沙班冻干口崩片及其制备方法；本发明中单位制剂中包括活性成分20mg～60mg，填充剂10mg～50mg，明胶10mg～50mg。本发明的冻干口崩片，口感良好，在口腔中10s内可迅速崩解，工艺简单易行，适于工艺化生产。

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公开/公告号CN112107551A

专利类型发明专利
公开/公告日2020-12-22

原文格式PDF
申请/专利权人北京万全德众医药生物技术有限公司;
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申请/专利号CN201910530540.3
发明设计人李春;王宇杰;
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申请日2019-06-19
分类号A61K9/20(20060101);A61K31/444(20060101);A61P7/02(20060101);
代理机构
代理人
地址 102206 北京市昌平区生命科学园博达大厦南楼
入库时间 2023-06-19 09:15:15

法律信息

法律状态公告日

法律状态信息

法律状态
2022-06-17

实质审查的生效 IPC(主分类):A61K 9/20 专利申请号:2019105305403 申请日:20190619

实质审查的生效

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1. 一种依度沙班冻干口崩片及其制备方法 [P] . 中国专利： CN112107551A . 2020-12-22
2. 一种高生物利用度的塞来昔布冻干口崩片及其制备方法 [P] . 中国专利： CN110840850A . 2020-02-28
3. bendamustine pharmaceutical composition, lyophilized preparation, pharmaceutical dosage form, method for obtaining official approval for a bendamustine product, process for making a lyophilized bendamustine preparation, bendamustine pre-lyophilization solution or dispersion, lyophilized powder, method for preparing a lyophilized preparation of bendamustine, formulation for lyophilization, and use of a pharmaceutically acceptable solution [P] . BRPI0606332A2 . 2009-11-17

机译：苯达莫司汀药物组合物，冻干制剂，药物剂型，获得苯达莫司汀产品官方批准的方法，冻干苯达莫司汀制剂的制备方法，苯达莫司汀预冻干溶液或分散液，冻干粉剂，苯达莫司汀冻干制剂的制备方法，制剂冻干的方法，以及可药用溶液的用途
4. Main invention of manufacturing method of the functional yogurt sprinkling for the salad designated the one for former boiled rice as entity, it sprinkles and being something which relates to the manufacturing method of the sprinkling which is functionality for the salad, if it displays the contents concisely, it seems the following way. (1) attaching in the vegetable salad, with the purpose which assures the improvement of nutrition functionality and acceptability, freeze-dry lyophilization (below FD it does) it added the powder yogurt. At the same time (2) it was tasty, ate the vegetable salad and easily in order to raise nutrition, the slice vegetable which is produced by FD, the fruit piece, the fragmentation nuts, it mixed the seasonings uniformly. Because (3) to powder is easy to mix the active yogurt which is converted equally, at the same time in the salad when using dissolution mildly to convert is easy, beforehand being added and mixing the asukorubin Acid, the non-fat dry mi [P] . 日本专利： JP4065998B2 . 2008-03-26

机译：沙拉用功能性酸奶洒水的制造方法的主要发明，是指以原煮米饭为主体的洒水，是关于沙拉的功能性的洒水的制造方法，只要其内容简洁地显示。，似乎是以下方式。（1）为了确保营养功能和可接受性的改善，在蔬菜沙拉中添加了冷冻酸奶冻干（低于FD）。同时（2）好吃，吃蔬菜沙拉容易并为了增加营养，用FD生产的切片蔬菜，水果片，碎坚果，将调味料均匀混合。（3）由于对粉末容易混合均匀转化的活性酸乳，同时在色拉中用溶解度轻度转化容易，同时预先加入和混合的asukorubin酸，脱脂干米粉混合即可。
5. lyophilized therapeutic peptibody composition, methods for making a lyophilized therapeutic peptibody and for preparing a lyophilized therapeutic peptibody composition and for preparing an aqueous pharmaceutical composition [P] . BRPI0710508A2 . 2012-10-30

机译：冻干的治疗性肽体组合物，制备冻干的治疗性肽体组合物的方法，冻干的治疗性肽体组合物的制备方法以及水性药物组合物的制备方法