The investigation of a fire in a well-confined and mechanically ventilated compartment is of primary importance for the nuclear industry. In normal operating conditions, a ventilation network system is set-up to ensure confinement via an appropriate pressure cascade. In the event of a fire, the subsequent pressure build-up alters the confinement level significantly and therefore changes the level of safety of the installation. The fire-induced pressure variations depend mainly on the: (1) HRR (Heat Release Rate) history of the fire, (2) heat losses to the walls, (3) leakage area, and (4) operating conditions of the fans. A numerical parametric analysis on the latter three parameters, using the Fire Dynamics Simulator (FDS 5.5.3), have shown that a change in the initial ventilation parameters (i.e. operating conditions of the fans and/or leaks), which can be sometimes difficult to determine, may lead to substantial changes in the pressure profiles. However, only a change in the thermal boundary conditions (i.e. presence or no of insulation) produces significant changes in the gas temperature.
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