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Point-of-care faecal calprotectin testing in patients with paediatric inflammatory bowel disease during the COVID-19 pandemic

机译:Covid-19大流行期间儿科炎症肠病患者的护理点粪便调节蛋白检测

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摘要

Objectives Following the disruption of normal paediatric inflammatory bowel disease (IBD) services during the peak of the COVID-19 pandemic, we prospectively audited the first-time use of home faecal calprotectin testing. We aimed to provide an alternative to laboratory tests and to assess the value of home testing as part of our regular services going forward.Methods Home test kits as well as accompanying user instructions were made available to our patients with paediatric IBD that required faecal calprotectin test between 17 April and 12 August 2020. Once the user completed the test, results were automatically uploaded to the result portal and clinical staff were alerted. A user feedback questionnaire was sent to users that had completed the home test.Results Of the 54 patients, 41 (76%) aged between 4.7 and 18.1 years used the home test. A total of 45 home tests were done, one of which produced an invalid result. The decision to modify management was made in 12 (29%) of the patients, while 14 (34%) had no changes made and 15 (37%) required further assessment. Twenty (48.8%) responded to the questionnaire and 85% stated that they preferred the home test to the laboratory testing method.Conclusions Home calprotectin tests were useful in guiding clinical management during a time when laboratory testing was less available. They may offer benefits as part of routine paediatric IBD monitoring to help target appointments and reduce unnecessary hospital attendances in the future.
机译:在Covid-19大流行的峰值期间发生普通小儿炎症肠病(IBD)服务后的目标,我们预先审核了首次使用家庭粪便CalProtectin测试。我们旨在提供实验室测试的替代方案,并评估家庭测试的价值,作为我们的常规服务的一部分。患有家庭测试套件以及随附的用户说明,我们的儿科IBD患者提供了粪便钙保护菌素测试在4月17日至8月12日之间。一旦用户完成了测试,结果将自动上传到结果门户网站,并提醒临床工作人员。用户反馈调查问卷被发送给已完成家庭测试的用户。54名患者的结果,41(76%)在4.7和18.1岁之间使用家庭测试。完成了45个家庭测试,其中一个是一个无效的结果。修改管理的决定是在12名(29%)的患者中进行,而14(34%)没有改变,15(37%)需要进一步评估。二十(48.8%)回应问卷和85%表示他们喜欢对实验室检测方法的家庭测试。结论家庭CalProtectin试验在实验室测试较少的时间期间指导临床管理。他们可以作为常规儿科IBD监测的一部分提供福利,以帮助目标约会,减少未来不必要的医院出席。

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