Statistical Issues in Clinical Trials for Treatment of Opiate Dependence

摘要

Contents: Drug Dependence (Addiction) and Its Treatment; Background and Design of a Controlled Clinical Trial (ARC 090) for the Treatment of Opioid Dependence; Clinical Endpoints: Discussion Session; Design of Clinical Trials for Treatment of Opiate Dependence: What is Missing; Efficacy of Urinalysis in Monitoring Heroin and Cocaine Abuse Patterns: Implications in Clinical Trials for Treatment of Drug Dependence; A Bayesian Nonparametric Approach to Analysis of Treatment for Drug Dependence Data; Three Estimators of the Probability of Opiate Use From Incomplete Data; Issues in the Analysis of Clinical Trials for Opiate Dependence; Analysis of Clinical Trials for Treatment of Opiate Dependence: What are the Possibilities; Toward a Dynamic Analysis of Disease-State Transition Monitored by Serial Clinical Laboratory Tests; A Markov Model for NIDA Data on Treatment of Opiate Dependence.