Literature-Related Discovery: Common Factors for Parkinson's Disease and Crohn's Disease

摘要

Literature-related discovery (LRD) is the linking of two or more literature concepts that have heretofore not been linked (i.e., disjoint), in order to produce novel, interesting, and intelligible knowledge (i.e., potential discovery). The mainstream software for assisting LRD is Arrowsmith. It uses text-based linkage to connect two disjoint literatures, and it generates intermediate linking literatures by matching title phrases from two disjoint literatures (literatures that do not share common records). Arrowsmith then prioritizes these linking phrases through a series of text-based filters. The present study examines another route to linking disjoint literatures (use of shared references, or, more generally, citation-based linkage) through a process called bibliographic coupling. Two disjoint literatures were selected for the demonstration: Parkinson's Disease (PD) (neurodegeneration) and Crohn's Disease (CD) (autoimmune). Three cases were examined: matching phrases in records with no shared references (text-based linkage only); shared references in records with no matching phrases (citation-based linkage only); matching phrases in records with shared references (text-based and citation-based linkages). In addition, the main themes in the body of shared references were examined through grouping techniques to identify the common themes between the two literatures.