The Role of a Newly Discovered Exotoxin (S Toxin) in 'Pseudomonas aeruginosa' Infections.

摘要

Exoenzyme S is an extracellular ADP-ribosyl transferase produced by some strains of P. aeruginosa. The authors have studied the production of S in vivo and in vitro and have partially purified S from culture supernatants of strain no. 388. This enzyme has been shown to differ from toxin A in (1) size, (2) substrate specificity, (3) thermal stability, (4) enzyme activation, and (5) nutritional requirements necessary for its production. (Author)