Direct Cobalt-Catalyzed Conjugate Addition of Functionalized Aryl Halides and Triflates: A New Strategy for the Conjugate Addition onto Methyl Vinyl Ketone

摘要

An efficient cobalt-catalyzed method for the direct con_jugate addition of functionalized aryl halides or triflates onto methyl vinyl ketone is described. The experimentally simple procedure re_lies on the use of a catalytic system consisting of CoBr_2(Bpy) and zinc and does not require the preformation of a stoichiometric orga_nometallic species. The approach described herein displays consid_erable functional-group compatibility at good to excellent yields.