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Epigenetics: A new science for middle school-and why you should teach it

机译:表观遗传学:中学的一门新科学-为什么要教它

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摘要

DNA is the command center of cells, but it does not act alone: Our environment plays a major role in the orders that DNA gives to direct how our cells function. We can think of DNA as a piano keyboard and our social and physical environments as the piano players. Surprisingly, DNA seems to be fluid, responding to environmental changes sometimes within as little as 15 minutes, and these changes can be lifelong. So, even though the keys on the DNA keyboard remain the same, the song it plays does not (Feinberg and Fallin 2015; Feil and Fraga 2012). This is especially evident during development. For example, some cells in the developing fetus turn into brain cells, whereas others turn into liver cells. Even though these cells have the same set of DNA, they are responding to different signals that, in total, create all the tissues in the body.
机译:DNA是细胞的指挥中心,但它并不单独起作用:我们的环境在DNA指导我们细胞功能的命令中起着重要作用。我们可以将DNA视为钢琴键盘,将社会和自然环境视为钢琴演奏者。令人惊讶的是,DNA似乎是流动的,有时在短短15分钟之内即可响应环境变化,而这些变化可能是终身的。因此,即使DNA键盘上的键保持不变,它所播放的歌曲也不相同(Feinberg和Fallin 2015; Feil和Fraga 2012)。这在开发期间尤其明显。例如,发育中的胎儿中的一些细胞会变成脑细胞,而另一些会变成肝细胞。即使这些细胞具有相同的DNA集,它们对不同的信号做出响应,这些信号总共会创建人体内的所有组织。

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