Autophagy SEPArates Germline and Somatic Cells

摘要

Cellular determinants of the germline selectively accumulate in germ cell precursors and influ_ence cell fate during early development in many organisms. Zhang et al. (2009) now report that targeted autophagy mediated by the SEPA-1 protein depletes germplasm proteins from somatic cells during early development of the nematode.