A novel FRET-based ratiometric fluorescent probe for highly sensitive detection of hydrogen sulfide

摘要

A novel FRET-based ratiometric fluorescent probe H2S-CR for the quantitative detection of H2S was designed and synthesized. It exhibits a response time of 20 min, a considerable fluorescence signal enhancement (15 fold), and an extremely low detection limit (19 nM). It can be successfully applied to imaging H2S in living cells.