Marketed formulations: Quality evaluation of conventional release paracetamol tablet

摘要

The main purpose of this work was to compare the quality of several marketed formulation and to evaluate the specifications laid down by FDA. Conventional release dosage forms are designed to achieve therapeutic effect by releasing drug over a short period of time after administration of dose. It allows the administration of dosage repeatedly in a day for short period of time as compared to extended release dosage form. The conventional paracetamol tablets were collected from market and evaluated for hardness, friability, weight variation, drug content, disintegration and in-vitro dissolution studies.