'FORMULATION amp; EVALUATION OF COLON TARGETING IMMEDIATE RELEASE MELOXICAM TABLET'

摘要

The present invention relates to a site-specific (colonic) pharmaceutical formulation prepared by direct compression method and sublimation technique for enhanced local absorption and improved bioavailability. The colon targeted immediate release tablet formulation contains Meloxicam as an active ingredient in pure, lyophilized, micronized or ß-cyclodextrin complex form in variable ratios along with superdisintegrant, other excipients, diluents, surfactant, glidant and lubricants. Formulation tablets are coated with eudragit S-100 polymer to achieve colon targeting.