Regulation der bei langandauerndem körperlichem Training beobachteten metabolischen Adaptation und Leistungssteigerung durch Thyreoidhormone

摘要

Rats in various states of thyroid, activity were subjected to a trainingprogram of strenuous swimming over a six week period. In normal animals a uniform pattern of mitochondrial enzymes (glycerol-phosphatdehydrogenase, succinatedehydrogenase, cytochrom a, b and c) has increased in specific activity and total amount in heart, liver and skeletal muscle. This is associated with an increased working capacity of the animals. These changes are absent in rats treated with Propylthiouracil, whereas administration of Triiodo-l-thyronine increased both investigated parameters over those of normal animals.