Vitiligo Potential Repigmentation Index: A simple clinical score that might predict the ability of vitiligo lesions to repigment under therapy

摘要

Madam, Nonsegmental vitiligo (NSV) is the most common form of vitiligo. Although its" exact pathogenesis is still to be fully understood, the depigmentation process is due to a progressive and chronic disappearance of epidermal and/or follicular mela-nocytes. Repigmentation of vitiligo lesions depends on the existence of available melanocytes from reservoirs located in the epidermis and the hair follicles. To date, there is no global method to evaluate the potential of repigmentation in NSV. We conducted a prospective observational study aiming to develop and validate a simple Potential Repigmentation Index (PRI), which could be useful in the daily management of patients with NSV. The study was approved by the local ethics committee of the Bordeaux University hospital.