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首页> 外文期刊>European journal of vascular and endovascular surgery: the official journal of the European Society for Vascular Surgery >Routine continuous cold perfusion of the kidneys during elective juxtarenal aortic aneurysm repair.
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Routine continuous cold perfusion of the kidneys during elective juxtarenal aortic aneurysm repair.

机译:择期近侧主动脉瘤修复过程中肾脏的常规连续冷灌注。

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摘要

OBJECTIVES: Surgical treatment of JAAs (juxtarenal aortic aneurysms) requires suprarenal aortic cross-clamping, causing temporary renal artery occlusion. We implemented a standardized protocol of hypothermic renal perfusion for all elective JAA operations. DESIGN: Retrospective study. MATERIALS AND METHODS: Over a period of 6 years, 23 consecutive patients received a 300ml bolus followed by an infusion (20ml/minute) of cold (4 degrees C) saline to each kidney during suprarenal aortic clamping. We assessed outcome in terms of rise in serum creatinine, new onset of dialysis and mortality. RESULTS: None of the patients suffered from postoperative acute renal failure and in-hospital mortality was zero. Five patients did not show any rise in serum creatinine level, whereas in the others rises were <25% in comparison with the admission level, except for one patient (38%). Postoperative rise in serum creatinine level was not related to renal ischemia time (Spearman rank correlation=0.24, p=0.27), preoperativerenal function, total aortic clamping time or renal re-implantation. There were no renal complications at 6 months. CONCLUSIONS: Our results suggest that a standardized strategy to apply renal hypothermia during the ischemic period of elective JAA surgery may reduce postoperative renal failure.
机译:目的:手术治疗JAAs(近侧主动脉瘤)需要进行肾上主动脉交叉钳夹术,从而导致暂时性肾动脉阻塞。我们为所有选择性JAA手术实施了低温肾灌注的标准化方案。设计:回顾性研究。材料与方法:在6年的时间里,连续23例患者接受300毫升推注,然后在肾上主动脉夹闭期间向每个肾脏输注(20毫升/分钟)冷(4摄氏度)生理盐水。我们根据血清肌酐升高,新发透析和死亡率评估了结局。结果:所有患者均无术后急性肾功能衰竭,院内死亡率为零。五名患者的血清肌酐水平未见任何升高,而其他患者的升高幅度与入院水平相比<25%,除了一名患者(38%)。术后血肌酐水平升高与肾脏缺血时间(Spearman等级相关= 0.24,p = 0.27),术前肾功能,总主动脉钳夹时间或肾脏再植入无关。 6个月时没有肾脏并发症。结论:我们的结果表明,在选择性JAA手术局部缺血期间应用肾脏低温治疗的标准化策略可减少术后肾衰竭。

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