Fibermalt is well tolerated in healthy men and women at intakes up to 60 g/d: a randomized, double-blind, crossover trial.

摘要

In this randomised, double-blind crossover trial, the digestive tolerance of a novel dietary fibre (fibermalt, an indigestible maltose alternan oligosaccharide) was assessed in healthy men and women. 29 subjects consumed 0 (control), 45 or 60 g of fibre in 2 doses/day for 2-wk treatment periods, each separated by a 2-wk washout. Results indicated no differences between treatments in composite gastrointestinal (GI) symptom scores (sum of 6 GI symptom ratings), individual GI symptoms (nausea, bloating, GI rumbling, gas/flatulence, abdominal pain and diarrhoea), bowel characteristics (frequency, faecal consistency, faecal hardness, straining, discomfort and incomplete evacuation) or average daily faecal output. The symptom scores were consistently low for each treatment period, with means averaging <1 out of a possible range of 0-12 for the composite score. Results suggested that fibermalt is well tolerated at intakes up to 60 g of fibre/day.