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首页> 外文期刊>Archives of orthopaedic and trauma surgery. >Elevated serum cardiac troponin I in older patients with hip fracture: incidence and prognostic significance.
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Elevated serum cardiac troponin I in older patients with hip fracture: incidence and prognostic significance.

机译:老年髋部骨折患者血清肌钙蛋白I升高:发生率和预后意义。

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We read with interest the article of Fischer et al. on incidence and significance of troponin levels in the course of hip fracture repair . We fully agree with their conclusion when they say that the troponin elevation is correlated with postoperative outcome. Indeed, several studies have shown that troponin release is a reliable marker of myocardial injury in the postoperative setting. Their introduction, however, leaves out a fair amount of data when they say that there is little agreement on the prognostic value of cardiac troponin in persons undergoing non-cardiac surgery [2-12]. Actually, several studies have been published on this issue.Most of them have focused on high risk patients, i.e. patients undergoing vascular surgery in whom the incidence of these events is extremely high. On these patients, serial troponin measurements are now the main diagnostic tool to detect myocardial ischaemia [7, 8]. Moreover, studies have shown a strong correlation between short-term troponin release and either postoperative complications or long-term cardiac complications, including death after vascular surgery [6, 7]. Thereafter, other studies have addressed the issue of the public health burden of myocardial ischaemia in major non-vascular surgery, especially in elderly patients [2, 9-12]. This concern is of great importance, since, even if the incidence of postoperative ischaemia in non-vascular surgery is low, the number of patients involved is extremely high [13].
机译:我们感兴趣地阅读了Fischer等人的文章。髋部骨折修复过程中肌钙蛋白水平的变化及其意义。当他们说肌钙蛋白升高与术后预后相关时,我们完全同意他们的结论。确实,一些研究表明,肌钙蛋白的释放是术后环境中心肌损伤的可靠标志。然而,当他们说心脏肌钙蛋白在非心脏手术患者的预后价值上并不一致时,他们的介绍却留下了大量的数据[2-12]。实际上,已针对此问题发表了几项研究,其中大多数研究针对的是高危患者,即接受血管外科手术的患者,这些事件的发生率极高。现在,对于这些患者,连续的肌钙蛋白测量是检测心肌缺血的主要诊断工具[7,8]。此外,研究表明短期肌钙蛋白释放与术后并发症或长期心脏并发症(包括血管手术后死亡)之间有很强的相关性[6,7]。此后,其他研究已经解决了大型非血管外科手术中心肌缺血的公共卫生负担问题,特别是在老年患者中[2,9-12]。这种关注非常重要,因为即使非血管外科手术后局部缺血的发生率较低,但涉及的患者数量却非常高[13]。

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