Development of immunotherapy with chimeric antigen receptor targeting intracellular WT1 gene product presented on HLA-A*24:02 molecule

Akahori Y.; Ikeda H.; Yoneyama M.; Orito Y.; Miyahara Y.; Amaishi Y.; Okamoto S.; Takesako K.; Mineno J.; Fujiwara H.; Yasukawa M.; Shiku H.

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Development of immunotherapy with chimeric antigen receptor targeting intracellular WT1 gene product presented on HLA-A*24:02 molecule

机译：用嵌合抗原受体靶向HLA-A * 24：02分子靶向嵌合抗原受体的免疫疗法的发展

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来源
《Human gene therapy》 |2015年第10期|共1页
作者
Akahori Y.; Ikeda H.; Yoneyama M.; Orito Y.; Miyahara Y.; Amaishi Y.; Okamoto S.; Takesako K.; Mineno J.; Fujiwara H.; Yasukawa M.; Shiku H.;
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作者单位

Mie Univ Grad Sch Med Tsu Mie Japan;

Takara Bio Inc Otsu Shiga Japan;

Mie Univ Grad Sch Med Tsu Mie Japan;

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正文语种 eng
中图分类治疗学;
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专利

1. Development of immunotherapy with chimeric antigen receptor targeting intracellular WT1 gene product presented on HLA-A*24:02 molecule [J] . Akahori Y., Ikeda H., Yoneyama M., Human gene therapy . 2015,第10期

机译：用嵌合抗原受体靶向HLA-A * 24：02分子靶向嵌合抗原受体的免疫疗法的发展
2. Development of chimeric antigen receptor (CAR) T-cell immunotherapy for glioblastoma targeting epidermal growth factor receptor variant III (EGFRvIII) [J] . Anthony K Park, Saul Priceman, Ethan Gerdts, Journal for ImmunoTherapy of Cancer . 2015,第S2期

机译：胶质母细胞瘤针对表皮生长因子受体变体III（EGFRvIII）的嵌合抗原受体（CAR）T细胞免疫疗法的开发
3. Adoptive immunotherapy with genetically engineered T cells: modification of the IgG1 Fc 'spacer' domain in the extracellular moiety of chimeric antigen receptors avoids 'off-target' activation and unintended initiation of an innate immune response. [J] . Hombach A, Hombach AA, Abken H Gene therapy . 2010,第10期

机译：基因工程T细胞的过继免疫疗法：嵌合抗原受体胞外部分中IgG1 Fc“间隔区”结构域的修饰避免了“脱靶”激活和先天免疫应答的意外启动。
4. REMOVAL OF MYELOID CELLS FROM AUTOLOGOUS LEUKOCYTES USED FOR CHIMERIC ANTIGEN RECEPTOR (CAR) T CELL MANUFACTURING IMPROVES FINAL PRODUCT CONSISTENCY AND YIELDS [C] . David Stroncek, Daniel W. Lee, Marianna Sabatino, Scale-up and manufacturing of cell-based therapies V . 2017

机译：从用于嵌合抗原受体（CAR）T细胞制造的自体白细胞去除髓样细胞可改善最终产品的一致性和产量
5. Targeting the Disialoganglioside GD2 with Chimeric Antigen Receptor T Cells for Immunotherapy in Diffuse Midline Gliomas, and Exploration of Neuron-OPC Synaptic Connectivity in the Context of Adaptive Myelination [D] . Mount, Christopher W. 2020

机译：用嵌合抗原受体T细胞靶向Diaialoganglioside GD2，用于在弥漫性中线胶质瘤中的免疫疗法，以及在适应性髓鞘中的背景下探索神经元-Popaptic连通性
6. An immunogenic WT1-derived peptide that induces T cell response in the context of HLA-A*02:01 and HLA-A*24:02 molecules [O] . Tao Dao, Tatyana Korontsvit, Victoria Zakhaleva, 2017

机译：在HLA-A * 02：01和HLA-A * 24：02分子的情况下诱导T细胞应答的WT1免疫原性肽
7. 393. Engineering Armored T Cell Receptor-Mimic (TCRm) Chimeric Antigen Receptor (CAR) T Cells Specific for the Intracellular Protein Wilms Tumor 1 (WT1) for Treatment of Hematologic and Solid Malignancies [O] . Sarwish Rafiq, Terence Purdon, Tao Dao, 2016

机译：393.工程铠装T细胞受体 - 模拟（TCRM）嵌合抗原受体（CAR）T细胞特异于细胞内蛋白肽肿瘤1（WT1），用于治疗血液管病和固体恶性肿瘤

Development of immunotherapy with chimeric antigen receptor targeting intracellular WT1 gene product presented on HLA-A*24:02 molecule

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