Quantification of peptides from immunoglobulin constant and variable regions by LC-MRM MS for assessment of multiple myeloma patients

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Quantification of peptides from immunoglobulin constant and variable regions by LC-MRM MS for assessment of multiple myeloma patients

机译：LC-MRM MS从免疫球蛋白常数和可变区的定量肽评估多发性骨髓瘤患者

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Purpose: Quantitative MS assays for Igs are compared with existing clinical methods in samples from patients with plasma cell dyscrasias, for example, multiple myeloma (MM).

机译：目的：将IGS的定量MS测定与来自血浆细胞功能困难患者的样品中的现有临床方法进行比较，例如多发性骨髓瘤（mm）。

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《Proteomics. Clinical applications》 |2014年第10期|共13页
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正文语种 eng
中图分类生物化学;
关键词
Ig quantification; LC-MRM MS; Multiple myeloma;

机译：IG量化;LC-MRM MS;多发性骨髓瘤;

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专利

1. Quantification of peptides from immunoglobulin constant and variable regions by LC-MRM MS for assessment of multiple myeloma patients [J] . Proteomics. Clinical applications . 2014,第9a10期

机译：LC-MRM MS从免疫球蛋白常数和可变区的定量肽评估多发性骨髓瘤患者
2. Monitoring M?Proteins in Patients with Multiple Myeloma Using Heavy-Chain Variable Region Clonotypic Peptides and LC?MS/MS [J] . David R. Barnidge, Renee C. Tschumper, Jason D. Theis, Journal of proteome research . 2014,第4期

机译：使用重链可变区克隆型肽和LC？MS / MS监测多发性骨髓瘤患者的M？蛋白
3. Analysis of the expressed immunoglobulin variable region heavy chain gene products in paraproteins from Iranian patients with multiple myeloma [J] . Fazel Shokri, Ramazan A. Sharifian, Rizgar A. Mageed, Pathology oncology research: POR . 2000,第3期

机译：伊朗多发性骨髓瘤患者副蛋白中表达的免疫球蛋白可变区重链基因产物的分析
4. Minimal Residual Disease In Multiple Myeloma By LC-MS/MS Analysis Of Immunoglobulin Heavy And Light Chain CDR Tryptic Peptides [C] . Linda M. Benson, Angela Dispenzieri, David Murray, ASMS Conference on Mass Spectrometry and Allied Topics . 2016

机译：通过LC-MS / MS分析免疫球蛋白重链CDR胰蛋白酶蛋白的LC-MS / MS分析，在多发性骨髓瘤中最小的残留疾病
5. Targeted Capture and Sequencing of Immunoglobulin Rearrangements in Multiple Myeloma to Enable Detection of Minimal Residual Disease [D] . Chow, Signy. 2017

机译：在多发性骨髓瘤中针对性捕获和免疫球蛋白重排测序，以检测出最小的残留疾病
6. Quantification of Peptides from Immunoglobulin Constant and Variable Regions by Liquid Chromatography-Multiple Reaction Monitoring Mass Spectrometry for Assessment of Multiple Myeloma Patients [O] . Elizabeth R. Remily-Wood, Kaaron Benson, Rachid C. Baz, -1

机译：液相色谱-多反应监测质谱法评估免疫球蛋白恒定区和可变区中的肽以评估多发性骨髓瘤患者
7. Immunoglobulin heavy chain gene organization in mice: Analysis of a myeloma genomic clone containing variable and α constant regions udud [O] . Early Philip W., Davis Mark M., Kaback David B., 1979

机译：小鼠免疫球蛋白重链基因组织：含有可变和α恒定区的骨髓瘤基因组克隆的分析 ud

Quantification of peptides from immunoglobulin constant and variable regions by LC-MRM MS for assessment of multiple myeloma patients

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