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A comparison of the nitrogen metabolic networks of Kluyveromyces marxianusKluyveromyces marxianus and Saccharomyces cerevisiaeSaccharomyces cerevisiae

机译：氮代谢网络的比较 kluyveromyces marxianus kluyveromyces marxianus和酿酒酵母（Saccharomyces cerevisiae）酿酒酵母

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Summary > In grape must, nitrogen is available as a complex mixture of various compounds (ammonium and amino acids). Wine yeasts assimilate these multiple sources in order to suitably fulfil their anabolic requirements during alcoholic fermentation. Nevertheless, the order of uptake and the intracellular fate of these sources are likely to differ between strains and species. Using a two‐pronged strategy of isotopic filiation and RNA sequencing, the metabolic network of nitrogen utilization and its regulation in Kluyveromyces marxianus were described, in comparison with those of Saccharomyces cerevisiae . The data highlighted differences in the assimilation of ammonium and arginine between the two species. The data also revealed that the metabolic fate of certain nitrogen sources differed, thereby resulting in the production of various amounts of key wine aroma compounds. These observations were corroborated by the gene expression analysis. </abstract> </span> <span class="z_kbtn z_kbtnclass hoverxs" style="display: none;">展开▼</span> </div> <div class="translation abstracttxt"> <span class="zhankaihshouqi fivelineshidden" id="abstract"> <span>机译：</span><Abstract Type =“Main”XML：Lang =“en”> <标题类型=“main”>概述</标题> >在葡萄中必须，氮可作为各种化合物的复杂混合物（铵和氨基酸）。葡萄酒酵母同化这些多种来源，以便在酒精发酵过程中适当地满足其合成代谢要求。尽管如此，这些来源的摄取顺序和这些来源的细胞内命例可能会在菌株和物种之间有所不同。使用两时间的同位素阳性策略和RNA测序，与酿酒酵母的酿酒酵母相比，描述了氮利用的代谢网络及其在 kluyveromycesmarxianus </ i>中的调节。数据突出显示两种物种之间铵和精氨酸的同化的差异。数据还显示出某些氮源的代谢命运不同，从而导致各种数量的关键葡萄酒芳香化合物的生产。通过基因表达分析证实了这些观察结果。 </ p> </ abstract> </span> <span class="z_kbtn z_kbtnclass hoverxs" style="display: none;">展开▼</span> </div> </div> <div class="record"> <h2 class="all_title" id="enpatent33" >著录项</h2> <ul> <li> <span class="lefttit">来源</span> <div style="width: 86%;vertical-align: text-top;display: inline-block;"> <a href='/journal-foreign-22868/'>《Environmental microbiology》</a> <b style="margin: 0 2px;">|</b><span>2019年第11期</span><b style="margin: 0 2px;">|</b><span>共16页</span> </div> </li> <li> <div class="author"> <span class="lefttit">作者</span> <p id="fAuthorthree" class="threelineshidden zhankaihshouqi"> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Rollero Stéphanie&option=202" target="_blank" rel="nofollow">Rollero Stéphanie;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Bloem Audrey&option=202" target="_blank" rel="nofollow">Bloem Audrey;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Ortiz‐Julien Anne&option=202" target="_blank" rel="nofollow">Ortiz‐Julien Anne;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Bauer Florian F.&option=202" target="_blank" rel="nofollow">Bauer Florian F.;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Camarasa Carole&option=202" target="_blank" rel="nofollow">Camarasa Carole;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Divol Benoit&option=202" target="_blank" rel="nofollow">Divol Benoit;</a> </p> <span class="z_kbtnclass z_kbtnclassall hoverxs" id="zkzz" style="display: none;">展开▼</span> </div> </li> <li> <div style="display: flex;"> <span class="lefttit">作者单位</span> <div style="position: relative;margin-left: 3px;max-width: 639px;"> <div class="threelineshidden zhankaihshouqi" id="fOrgthree"> <p>Institute for Wine Biotechnology Department of Viticulture and OenologyStellenbosch UniversityStellenbosch South Africa;</p> <p>UMR SPO INRA SupAgroMUniversité de MontpellierMontpellier France;</p> <p>Lallemand Inc.Montreal QC Canada;</p> <p>Institute for Wine Biotechnology Department of Viticulture and OenologyStellenbosch UniversityStellenbosch South Africa;</p> <p>UMR SPO INRA SupAgroMUniversité de MontpellierMontpellier France;</p> <p>Institute for Wine Biotechnology Department of Viticulture and OenologyStellenbosch UniversityStellenbosch South Africa;</p> </div> <span class="z_kbtnclass z_kbtnclassall hoverxs" id="zhdw" style="display: none;">展开▼</span> </div> </div> </li> <li > <span class="lefttit">收录信息</span> <span style="width: 86%;vertical-align: text-top;display: inline-block;"></span> </li> <li> <span class="lefttit">原文格式</span> <span>PDF</span> </li> <li> <span class="lefttit">正文语种</span> <span>eng</span> </li> <li> <span class="lefttit">中图分类</span> <span><a href="https://www.zhangqiaokeyan.com/clc/183.html" title="微生物学">微生物学;</a></span> </li> <li class="antistop"> <span class="lefttit">关键词</span> <p style="width: 86%;vertical-align: text-top;"> </p> </li> </ul> </div> </div> <div class="literature cardcommon"> <div class="similarity "> <h3 class="all_title" id="enpatent66">相似文献</h3> <div class="similaritytab clearfix"> <ul> <li class="active" >外文文献</li> <li >中文文献</li> <li >专利</li> </ul> </div> <div class="similarity_details"> <ul > <li> <div> <b>1. </b><a class="enjiyixqcontent" 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target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,韩锡铜</a> <span> <a href="/journal-cn-5081/" target="_blank" rel="nofollow" class="tuijian_authcolor"> . 生物加工过程 </a> </span> <span> . 2012</span><span>,第005期</span> </span> </div> </li> <li> <div> <b>5. </b><a class="enjiyixqcontent" href="/academic-journal-cn_food-fermentation-industries_thesis/020123255064.html">Kluyveromyces marxianus菊粉外切酶的制备及其水解菊粉的研究</a> <b>[J]</b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=汪伦记&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . 汪伦记</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=董英&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,董英</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=邹风&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,邹风</a> <span> <a href="/journal-cn-9397/" target="_blank" rel="nofollow" class="tuijian_authcolor"> . 食品与发酵工业 </a> </span> <span> . 2009</span><span>,第011期</span> </span> </div> </li> <li> <div> <b>6. </b><a class="enjiyixqcontent" href="/academic-conference-cn_meeting-8131_thesis/020222084126.html">Kluyveromyces marxianus中真菌来源的木糖异构酶的功能表达及其在高温下对发酵木糖的研究</a> <b>[C]</b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=汪荣亮&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . 汪荣亮</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=李璐璐&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,李璐璐</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=张标&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,张标</a> <span> <a href="/conference-cn-8131/" target="_blank" rel="nofollow" class="tuijian_authcolor"> . 纪念中国微生物学会成立六十周年大会暨2012年中国微生物学会学术年会 </a> <span> <span> . 2012</span> </span> </div> </li> <li> <div> <b>7. </b><a class="enjiyixqcontent" href="/academic-degree-domestic_mphd_thesis/020311788559.html">Kluyveromyces marxianus GX-15 ADH1基因的克隆、表达及重组蛋白酶学性质研究</a> <b>[A] </b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=麦志茂&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . 麦志茂</a> <span> . 2011</span> </span> </div> </li> </ul> <ul style="display: none;"> <li> <div> <b>1. </b><a class="enjiyixqcontent" href="/patent-detail/061201426354.html">通过原生质体融合得到的乙醇抗性酿酒酵母(Saccharomyces cerevisiae)GP-01,其生产方法,通过利用酿酒酵母GP-01和作为锗来源的高水溶性偏锗酸钠生产包含高含量生物有机锗的酵母的方法</a> <b>[P]</b> . <span> 中国专利： CN102239246B </span> <span> . 2014.07.23</span> </div> </li> <li> <div> <b>2. </b><a class="enjiyixqcontent" href="/patent-detail/06120106446366.html">通过原生质体融合得到的乙醇抗性酿酒酵母(Saccharomyces cerevisiae)GP-01,其生产方法,通过利用酿酒酵母GP-01和作为锗来源的高水溶性偏锗酸钠生产包含高含量生物有机锗的酵母的方法</a> <b>[P]</b> . <span> 中国专利： CN102239246A </span> <span> . 2011-11-09</span> </div> </li> <li> <div> <b>3. </b><a class="enjiyixqcontent" href="/patent-detail/06130418142967.html">GENOME-SCALE METABOLIC NETWORK MODEL RECONSTRUCTION OF KLUYVEROMYCES MARXIANUS AND STRATEGIES FOR ENGINEERING NON-NATIVE PATHWAYS FOR 3-HYDROXYPROPIONATE PRODUCTION IN KLUYVEROMYCES MARXIANUS</a> <b>[P]</b> . <span> 外国专利： <!-- 美国专利： --> US2014093901A1 </span> <span> . 2014-04-03</span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：马克斯克鲁维酵母基因组规模代谢网络模型的重构及非天然途径生产马克斯克鲁维酵母的3-羟基丙酸酯的工程化策略 </span> </p> </li> <li> <div> <b>4. </b><a class="enjiyixqcontent" href="/patent-detail/06130416858058.html">GENOME-SCALE METABOLIC NETWORK MODEL RECONSTRUCTION OF KLUYVEROMYCES MARXIANUS AND STRATEGIES FOR ENGINEERING NON-NATIVE PATHWAYS FOR 3-HYDROXYPROPIONATE PRODUCTION IN KLUYVEROMYCES MARXIANUS</a> <b>[P]</b> . <span> 外国专利： <!-- 韩国专利： --> KR20140015998A </span> <span> . 2014-02-07</span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：马克斯克鲁维酵母基因组规模代谢网络模型的重构及非天然途径生产马克斯克鲁维酵母的3-羟基丙酸酯的工程化策略 </span> </p> </li> <li> <div> <b>5. </b><a class="enjiyixqcontent" href="/patent-detail/06130421094021.html">The method of expression of the gene of interest to be used in the Kluyveromyces marxianus, the promoter of specific derived from Saccharomyces cerevisiae</a> <b>[P]</b> . <span> 外国专利： <!-- 日本专利： --> JPWO2011099243A1 </span> <span> . 2013-06-13</span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：啤酒酵母特异基因的启动子马克斯克鲁维酵母中所用目标基因的表达方法 </span> </p> </li> </ul> </div> </div> </div> <div class="theme cardcommon" style="overflow: auto;display:none"> <h3 class="all_title" id="enpatent55">相关主题</h3> <ul id="subject"> </ul> </div> </div> </div> </div> <div class="right 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