Catechol-O-methyltransferase Gene Polymorphism (Val158Met) and Development of Pre-eclampsia

摘要

Objectives. Catechol-O-methyltransferase (COMT) is a key enzyme in degradation pathways of estrogens and catecholamines. The present meta-analysis was done to elucidate the association of COMT Val158Met polymorphism with pre-eclampsia among pregnant women.