The early effect of sunitinib on insulin clearance in patients with metastatic renal cell carcinoma

Thijs Anna Maria J.; Tack Cees J.; van der Graaf Winette T. A.; Rongen Gerard A.; van Herpen Carla M. L.

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The early effect of sunitinib on insulin clearance in patients with metastatic renal cell carcinoma

机译：仙色inib对转移性肾细胞癌患者胰岛素清除的早期作用

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AimsIn patients with diabetes treated with sunitinib symptomatic hypoglycaemia has been reported. To explore the mechanism of this adverse effect we performed a prospective study to investigate the effect of sunitinib on insulin concentration, insulin clearance and insulin sensitivity.

机译：据报道，旨在患有Sunitinib症状低血糖治疗的糖尿病患者。为了探讨这种不利影响的机制，我们进行了一个前瞻性研究，探讨了Sunitinib对胰岛素浓度，胰岛素清除和胰岛素敏感性的影响。

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来源
《British Journal of Clinical Pharmacology》 |2016年第4期|共5页
作者
Thijs Anna Maria J.; Tack Cees J.; van der Graaf Winette T. A.; Rongen Gerard A.; van Herpen Carla M. L.;
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作者单位

Radboudumc Dept Pharmacol Toxicol Nijmegen Netherlands;

Radboudumc Dept Internal Med Nijmegen Netherlands;

Radboudumc Dept Med Oncol Nijmegen Netherlands;

Radboudumc Dept Pharmacol Toxicol Nijmegen Netherlands;

Radboudumc Dept Med Oncol Nijmegen Netherlands;

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原文格式 PDF
正文语种 eng
中图分类药理学;
关键词
diabetes; hypoglycaemia; insulin; renal cell carcinoma; sunitinib; tyrosine kinase inhibitor;

机译：糖尿病;低血糖;胰岛素;肾细胞癌;瑞尼尼;酪氨酸激酶抑制剂;
入库时间 2022-08-19 23:13:42

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1. The early effect of sunitinib on insulin clearance in patients with metastatic renal cell carcinoma [J] . Thijs Anna Maria J., Tack Cees J., van der Graaf Winette T. A., British Journal of Clinical Pharmacology . 2016,第4期

机译：舒尼替尼对转移性肾细胞癌患者胰岛素清除的早期作用
2. The early effect of sunitinib on insulin clearance in patients with metastatic renal cell carcinoma [J] . Thijs Anna Maria J., Tack Cees J., van der Graaf Winette T. A., British Journal of Clinical Pharmacology . 2016,第4期

机译：仙色inib对转移性肾细胞癌患者胰岛素清除的早期作用
3. Reply to Michael Staehler, Dena Battle, Axel Bex, Hans Hammers, and Daniel George's Letter to the Editor re: Arnaud Mejean, Alain Ravaud, Simon Thezenas, et al. Sunitinib Alone or After Nephrectomy in Metastatic Renal-cell Carcinoma. Eur Urol 2018;74:842-3 Lymphocyte Phenotype and Timing of Radical Nephrectomy in Patients Treated with Immunocheckpoint Inhibitors for Renal Cell Carcinoma [J] . Santoni Matteo, Montironi Rodolfo, Battelli Nicola, European urology . 2019,第3期

机译：回复Michael Staehler，Dena Battle，Axel Bex，Hans Hammers和Daniel George的信Re：Arnaud Mejean，Alain Ravaud，Simon Thezenas，等。单独的Sunitinib或在转移性肾细胞癌中肾切除术后。 EUR UROL 2018; 74：842-3淋巴细胞表型和自由基肾切除术治疗肾细胞癌治疗的患者的激进肾切除术
4. When to Treat Metastatic Renal Cell Carcinoma Comorbidities, Systemic Therapy, and Active Surveillance in Metastatic Kidney Cancer [C] . Brian I. Rini Genitourinary Cancers Symposium . 2012

机译：何时治疗转移性肾细胞癌的组合，全身治疗，以及在转移性肾癌中的活跃监测
5. Methodological Approaches for Conducting Claims-Based Studies in Patients Diagnosed with Metastatic Renal Cell Carcinoma [D] . Chun, Danielle S. 2021

机译：用于诊断转移性肾细胞癌的患者的基于权利要求的基于权利要求的方法论方法
6. The early effect of sunitinib on insulin clearance in patients with metastatic renal cell carcinoma [O] . Anna Maria J. Thijs, Cees J. Tack, Winette T. A. van der Graaf, 2016

机译：舒尼替尼对转移性肾细胞癌患者胰岛素清除的早期作用
7. MP16-01 CLINICAL IMPLICATIONS OF SUNITINIB AND N-DESETHYL-SUNITINIB PLASMA CONCENTRATIONS FOR TREATMENT OUTCOME IN METASTATIC RENAL CELL CARCINOMA PATIENTS [O] . Kazuyuki Numakura, Nobuhiro Fujiyama, Makoto Takahashi, 2017

机译：MP16-01 Sunitinib和N-脱乙基 - Sunitinib血浆浓度治疗转移肾细胞癌患者治疗结果的临床意义

The early effect of sunitinib on insulin clearance in patients with metastatic renal cell carcinoma

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